Looking for latest science?
There are 173 published clinical (human) studies on K2 according to a Pubmed search. Many of them are sponsored and published by academia bodies, not private companies.
The results of these studies are copyrighted, however quoting small sections that are directly relevant to something one is writing about is acceptable under Fair Use, as long as one provides an appropriate citation. Summarizing and quoting from a medical article in a news article (Commentary, Criticism, “transformative” purpose) is considered a fair use according to this source. All human clinical studies were designed and performed on Menaquinone-7 chemical compound which does not differ in terms of bioavailability or safety profile regardless if obtained through organic synthesis or biochemistry (industrial fermentation). Vitamin K2 offered in the market differs only in terms of purity offered and presentation oil, powder, microcapsule. We encourage all our clients to produce educational content based on the available study results and fair use policy. In case of advertising of a specific brand, use of third-party study results is prohibited.
Read more...
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
TITLE
The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis
CATEGORY
Hormonal & Menopause Health
DATE
Nov 2025
KEYWORDS
bone metabolism; bone turnover markers; meta-analysis; osteocalcin; osteoporosis; ucOC; vitamin K2
TITLE
Efficacy of Recombinant Human Parathyroid Hormone 1-34 and Vitamin K2 Combination Therapy in Postmenopausal Osteoporosis
CATEGORY
Hormonal & Menopause Health
DATE
Jan 2025
KEYWORDS
postmenopausal osteoporosis - recombinant human parathyroid hormone 1-34 - vitamin K2 - BMD - bone metabolism
TITLE
Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review
CATEGORY
Hormonal & Menopause Health
DATE
Sep 2022
KEYWORDS
BMD; Osteocalcin; Osteoporosis; Undercarboxylated osteocalcin; Vitamin K2
TITLE
Efficacy of vitamin K2 in the prevention and treatment of postmenopausal osteoporosis: A systematic review and meta-analysis of randomized controlled trials
CATEGORY
Hormonal & Menopause Health
DATE
Aug 2022
KEYWORDS
fracture; meta-analysis; osteoporosis; postmenopausal women; randomized controlled trial; vitamin K2
TITLE
Vitamin K2 (menaquinone-7) prevents age-related deterioration of trabecular bone microarchitecture at the tibia in postmenopausal women.
CATEGORY
Hormonal & Menopause Health
DATE
Dec 2016
KEYWORDS
bone mineral density calcium menaquinone-7 osteopenia postmenopausal women vitamin D vitamin K2
TITLE
Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
CATEGORY
Hormonal & Menopause Health
DATE
May 2014
KEYWORDS
bone loss bone metabolism bone mineral density menaquinone-4 postmenopausal women vitamin K2
TITLE
Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
CATEGORY
Hormonal & Menopause Health
DATE
Sep 2013
KEYWORDS
"bone loss bone mineral density menaquinone-7 postmenopausal women vitamin K2"
TITLE
Possible site-specific effect of an intervention combining nutrition and lifestyle counselling with consumption of fortified dairy products on bone mass: the Postmenopausal Health Study II.
CATEGORY
Hormonal & Menopause Health
DATE
Jul 2011
KEYWORDS
bone mineral density calcium menaquinone-7 phylloquinone postmenopausal women vitamin D3 vitamin K1 vitamin K2
TITLE
Vitamin K2 supplementation does not influence bone loss in early menopausal women: a randomised double-blind placebo-controlled trial.
CATEGORY
Hormonal & Menopause Health
DATE
Oct 2010
KEYWORDS
"bone loss early menopausal women menaquinone-7 vitamin K2"
TITLE
Vitamin K treatment reduces undercarboxylated osteocalcin but does not alter bone turnover, density, or geometry in healthy postmenopausal North American women.
CATEGORY
Hormonal & Menopause Health
DATE
Jun 2009
KEYWORDS
bone health menaquinone-4 phylloquinone postmenopausal women vitamin K1 vitamin K2
TITLE
Effect of low dose vitamin K2 (MK-4) supplementation on bio-indices in postmenopausal Japanese women.
CATEGORY
Hormonal & Menopause Health
DATE
Feb 2009
KEYWORDS
bone metabolism menaquinone-4 postmenopausal women vitamin K2
TITLE
Vitamin K2 treatment for postmenopausal osteoporosis in Indonesia
CATEGORY
Hormonal & Menopause Health
DATE
Apr 2006
KEYWORDS
bone mineral density, menatetrenone, osteocalcin, osteoporosis, postmenopause
TITLE
Promotion of bone formation by fermented soybean (Natto) intake in premenopausal women
CATEGORY
Hormonal & Menopause Health
DATE
Apr 2004
KEYWORDS
premenopausal women , Natto intake, stiffness index, bone formation marker, vitamin K2
TITLE
Menatetrenone versus alfacalcidol in the treatment of Chinese postmenopausal women with osteoporosis: a multicenter, randomized, double-blinded, double-dummy, positive drug-controlled clinical trial
CATEGORY
Hormonal & Menopause Health
DATE
Jul 1905
KEYWORDS
alfacalcidol; bone mineral density; menatetrenone; osteoporosis; postmenopausal; undercarboxylated osteocalcin
TITLE
Short-term menatetrenone therapy increases gamma-carboxylation of osteocalcin with a moderate increase of bone turnover in postmenopausal osteoporosis: a randomized prospective study
CATEGORY
Hormonal & Menopause Health
DATE
Jul 1905
KEYWORDS
Menatetrenone, Osteoporosis, Undercarboxylated osteocalcin, Bone turnover markers
TITLE
Response of serum carboxylated and undercarboxylated osteocalcin to alendronate monotherapy and combined therapy with vitamin K2 in postmenopausal women
CATEGORY
Hormonal & Menopause Health
DATE
Jun 1905
KEYWORDS
alendronate, osteocalcin, postmenopausal woman, vitamin K2
TITLE
Effect of menatetrenone on bone mineral density and incidence of vertebral fractures in postmenopausal women with osteoporosis: a comparison with the effect of etidronate
CATEGORY
Hormonal & Menopause Health
DATE
Jun 1905
KEYWORDS
Menatetrenone, Etidronate, Osteoporosis, Bone mineral density (BMD), Vertebral fracture
